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2019년 중국 우한 코로나바이러스 감염 환자 사망률과 방사선 소견연구(Association of radiologic findings with mortality of patient


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2019년 중국 우한 코로나바이러스 감염 환자 사망률과 방사선 소견연구(Association of radiologic findings with mortality of patient

Mingli Yuan, Wen Yin, Zhaowu Tao, Weijun Tan, Yi Hu 저 | 아진

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2020-07-14
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한줄서평

콘텐츠 소개

Radiologic characteristics of 2019 novel coronavirus (2019-nCoV) infected
pneumonia(NCIP) which had not been fully understood are especially important for
diagnosing and predicting prognosis. We retrospective studied 27 consecutive
patients who were confirmed NCIP, the clinical characteristics and CT image
findings were collected, and the association of radiologic findings with mortality of
patients was evaluated. 27 patients included 12 men and 15 women, with median
age of 60 years (IQR 47?69). 17 patients discharged in recovered condition and 10
patients died in hospital. The median age of mortality group was higher compared
to survival group (68 (IQR 63?73) vs 55 (IQR 35?60), P = 0.003).
The comorbidity rate in mortality group was significantly higher than in survival
group (80% vs 29%, P = 0.018). The predominant CT characteristics consisted of
ground glass opacity(67%), bilateral sides involved (86%), both peripheral and
central distribution (74%), and lower zone involvement (96%). The median CT score
of mortality group was higher compared to survival group (30 (IQR 7?13) vs 12
(IQR 11?43), P = 0.021), with more frequency of consolidation (40% vs 6%, P =
0.047) and air bronchogram (60% vs 12%, P = 0.025).
An optimal cutoff value of a CT score of 24.5 had a sensitivity of 85.6% and a
specificity of 84.5% for the prediction of mortality. 2019-nCoV was more likely to
infect elderly people with chronic comorbidities. CT findings of NCIP were featured
by predominant ground glass opacities mixed with consolidations, mainly peripheral
or combined peripheral and central distributions, bilateral and lower lung zones
being mostly involved. A simple CT scoring method was capable to predict
mortality.

목차

제 1편 : 코로나-19의 정의
1. 코로나바이러스감염증-19(COVID-19) 정보 7
2. 코로나바이러스 분류 및 특성 9
3. 코로나 바이러스 전자현미경 형태 11
4. 코로나바이러스 구조 (Covid-19 Organization) 13
5. 코로나19: 환경에 지속적인 영향을 미칠까? 19
6. 치료법(Therapeutical Method) 22
제 2편 : 연구논문
Association of radiologic findings with mortality of patients infected
with 2019 novel coronavirus in Wuhan, China
Abstract 23
Introduction 23
Methods 24
Results 27
Discussion 29
References 31

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